The mRNA-LNP lab,
from sequence to in vivo.

On-demand services, all in one lab:

  • mRNA & LNP design
  • Manufacturing & QC
  • In vitro testing
  • In vivo preclinical testing

Idea to preclinical data in as little as 6 weeks.

  • Melbourne, Australia
  • Customers in 22 countries
  • 100+ institutions

Build your own wet lab pipeline

mRNA design, manufacturing, LNP formulation, in vitro screening and in vivo testing, run end to end by one team.
Use the full pipeline or only the stages you need.

  1. SEQUENCE ✓ Optimised StabilityTranslationImmunogenicity

    Design

    Optimise your sequence & confirm manufacturing requirements

    Results
    • Optimised mRNA sequence
    • Manufacturing and QC specification
    • Study design and quote
  2. Build

    Manufacture mRNA, formulate LNPs and run QC assays.

    Results
    • mRNA and LNPs, ready to use
    • QC report: integrity, purity, dsRNA
    • LNP size, PDI and encapsulation
  3. Lead candidate

    Screen

    Evaluate expression and function in vitro.

    Results
    • In vitro expression and function data
    • Lead candidate selection
  4. BIODISTRIBUTION Expression (a.u.) 101102103104105 LiverSpleenLungHeartKidney

    Test

    Assess efficacy, safety and biodistribution in vivo.

    Results
    • In vivo efficacy and safety data
    • Biodistribution by organ
    • Full study report
    About our in vivo testing →

Built by mRNA
scientists for
mRNA programs.

Every project adds to the platform. We protect each customer's privacy and use what we learn to improve the work we do for the next one.

01

Flexible by design

Use us for one stage or all four. We fit the scope to your requirements.

02

Speed to data

Design, synthesise, test, evaluate. All mRNA synthesis, LNP formulation and testing is done here in Australia.

03

One partner, full cycle

From first design to in vivo evaluation. No hand-offs between CROs, no lost context.

A well-validated LNP toolkit for your RNA.

Encapsulate your RNA in LNPs optimised for your research:

  • Benchmark ionisable lipids
  • Well-characterised safety profiles
  • Novel formulations
  • Designed for specific targets
5+well-known lipids, plus others on request
3payloads: mRNA, siRNA and gRNA
tLNPsAdd a targeting moiety for optimised delivery
Co-formulateFormulate multiple RNAs together, e.g. Cas9 mRNA + gRNA
Build your LNP
PayloadmRNA
LipidSM-102
ClassIonisable

SM-102ALC-0315MC3LP01DOTAP+ other ionisable lipids

One partner.
Fewer bottlenecks.

Most mRNA programs piece together separate suppliers, often in different countries. We do it all in one lab in Melbourne, to one high standard, and one team answers for the result.

Who does the work
Separate vendors for design, mRNA, LNPs and testing
One team, from design to data
Where it happens
Sites in different cities, countries and time zones
One lab in Melbourne, Australia
Between stages
Material shipped cold between sites and re-checked at each stop
Material never leaves the lab
Standards
Quality varies from one vendor to the next
One high standard, applied at every stage
Accountability
Each vendor answers only for its own step
One team accountable for the whole result
Your IP and data
Different terms with every vendor
Retain your IP. Own your data.
Retain your IP. Own your data.

Your sequences and your results stay yours. Use the whole pipeline, or only the stages you need.

Plan your project →

Start from a product, or from a sequence.

Have a project in mind?

Tell us what you're working on. One of our scientists will get back to you within 48 hours.

Contact us → or email hello@messenger.bio

Have a project in mind?

Email us at help@messenger.bio or use the form below.