Embark™️ mRNA Purification Kit (removes dsRNA)

from A$600.00

CATALOG #

EMBARK25: 25-column mRNA Purification Kit
EMBARK50: 50-column mRNA Purification Kit
EMBARK100: 100-column mRNA Purification Kit

(To pay with a purchase order, please send your purchase order to sales@messenger.bio.)

Need pure mRNA but want to DIY? Messenger Bio's Embark™️ mRNA Purification Kit is designed for rapid and reliable purification of mRNA after in vitro transcription. The Embark™️ kit enables removal of all major reaction contaminants, including dsRNA contaminants which almost all other kits fail to remove.

Each kit comes with:

  • 8 M Lithium Chloride for isolating mRNA after transcription

  • 25, 50 or 100 pre-prepared purification columns

  • mRNA Purification Buffer

  • 3 M Sodium Acetate (pH 5.2–5.5) for isolating mRNA after purification (you will need to supply your own isopropanol)

  • 1 mM Citrate Buffer (pH 6.5) for resuspension of mRNA after isolation

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“I have been using this kit to remove ds-RNA contaminants as I inject the mRNA into mice. I had seen before that using traditional kits led to non-specific immune response as observed by substantial increase in cytokines like IL-6. Using this kit, the issue seems to be resolved as ds-RNA contaminants are removed.” 

- Chaitanya Naimesh Parikh, UMass Chan Medical School