Nanoluc mRNA
Available in 3 options:
Naked mRNA (price displayed below)
mRNA + LNP (ready to transfect)*
mRNA + LNP mixture (DIY assembly of LNPs)*
*For pricing contact hello@messenger.bio
CATALOG #
NANOL50U: 50 µg unmodified NanoLuc mRNA
NANOL100U: 100 µg unmodified NanoLuc mRNA
NANOL500U: 500 µg unmodified NanoLuc mRNA
NANOL1000U: 1 mg unmodified NanoLuc mRNA
NANOL50P: 50 µg N1-methylpseudouridine base-modified NanoLuc mRNA
NANOL100P: 100 µg N1-methylpseudouridine base-modified NanoLuc mRNA
NANOL500P: 500 µg N1-methylpseudouridine base-modified NanoLuc mRNA
NANOL1000P: 1 mg N1-methylpseudouridine base-modified NanoLuc mRNA
NANOL50M: 50 µg 5-methoxyuridine base-modified NanoLuc mRNA
NANOL100M: 100 µg 5-methoxyuridine base-modified NanoLuc mRNA
NANOL500M: 500 µg 5-methoxyuridine base-modified NanoLuc mRNA
NANOL1000M: 1 mg 5-methoxyuridine base-modified NanoLuc mRNA
(To pay with a purchase order, please send your purchase order to sales@messenger.bio.)
Our NanoLuc mRNA has been specially designed for maximal in vitro expression and luminescence. NanoLuc is smaller than typical luciferases and when combined with the appropriate substrate, produces a brighter luminescence than firefly luciferase.
We have engineered our NanoLuc mRNA to include a Cap1 structure (biologically superior to Cap0), a highly expressing 5’ UTR and highly stable 3’ UTR, a 100-nt poly(A) tail, and a codon-optimized luciferase open reading frame. Choose from unmodified or modified (N1-methylpseudouridine or 5-methoxyuridine) bases. Both types of modified bases have been shown to enhance protein expression in vitro and in vivo.
Our robust purification process removes dsRNA contaminants and other reaction components, generating highly pure mRNA that is capable of inducing very high levels of protein expression in diverse cell types, while causing minimal cellular innate immune activation (virtually undetectable).
As with all our mRNAs, this NanoLuc mRNA comes ready-to-use in a 1 mM sodium citrate buffer (pH 6.5), which is ideal for preserving RNA stability and extending shelf-life. Just complex with your favorite transfection reagent and you’re ready to go.
If you would like to request a different amount of mRNA than what is listed on our website, or a different type of modified base, or any more information about our NanoLuc mRNA, send us an email at hello@messenger.bio and we’ll be happy to help.
For Research Use Only. See Terms of Sale for more.
